HIV-positive people taking antiretroviral therapy who have an undetectable viral load and a CD4 cell count above 500 cells/mm3 have a mortality risk comparable to that seen in the general population, investigators report in the online edition of AIDS. Researchers looked at mortality rates among participants enrolled in two large, randomised controlled trials – the SMART and ESPRIT studies.
In 2011 werden 5.364 meldingen geregistreerd van de seksueel overdraagbare aandoeningen (soa) syfilis, gonorroe en chlamydia. Dat zijn er meer dan in 2010 (4.617). Sinds 2008 (3.930 meldingen) steeg het aantal met 36,1 procent.
Only one-in-six men reported 100% condom use during three to four years of follow-up.
An analysis by Dawn Smith of the US Centers for Disease Control (CDC) reported at the 20th Conference on Retroviruses and Opportunistic Infections (CROI 2013) on 4 March has provided the first estimate of the efficacy of condoms in preventing HIV transmission during anal sex since 1989. It found condoms stop seven out of ten anal transmissions – the same efficacy found by the 1989 study.
However, it also found that sometimes using condoms is not effective at preventing HIV infection, and that long-term 100% condom use is a minority behaviour: only one-in-six gay men actually managed to maintain it over the three- to four-year time frame of the analysis.
Mortality in people with HIV is continuing to fall, Swiss investigators report in HIV Medicine. The mortality rate in 2010 was a little over 1% and the majority of deaths were due to non-AIDS-related causes, many of which were associated with modifiable risk factors.
Effectiveness depends on regular screening for viral load rebounds & STI's.
The British HIV Association (BHIVA) and the Department of Health's Expert Advisory Group on AIDS ( EAGA) published this week a position statement on the use of HIV treatment by people with HIV to reduce the risk of transmission. For the first time, the document provides health professionals with a consensus statement, developed by UK experts, which can be used to guide discussions with individuals. Clinicians, epidemiologists, policy experts and HIV-positive people contributed to the document. The key points are outlined below.
In high-income countries such as Canada, Australia and the U.S. and regions such as Western Europe, screening of the blood supply has virtually eliminated transmission of hepatitis C virus (HCV) via blood transfusions. In these countries and regions HCV is now mostly transmitted in the following ways:
New Swiss research has shown the benefits of treating hypertension in HIV-positive people. The investigators calculated that the reduction in blood pressure achieved by their patients would “significantly reduce cardiovascular endpoints”. Traditional, rather than HIV-associated, risk factors were associated with increases in blood pressure.